Abstract Solid tumors are complex entities that actively shape their microenvironment to create a supportive environment for their own growth.Angiogenesis and immune suppression are two key characteristics of this tumor microenvironment.Despite attempts to deplete tumor blood vessels using antiangiogenic drugs, extensive vessel pruning has shown li
Structural Maintenance of Chromosomes (SMC) family proteins participate in multisubunit complexes that govern chromosome structure and dynamics.SMC-containing condensin complexes create chromosome topologies essential for mitosis/meiosis, gene expression, recombination, and repair.Many eukaryotes have two condensin complexes (I and II); C.elegans h
Central diabetes insipidus (DI) is a known complication associated with pituitary surgeries occurring in postoperative period.However, development of DI following aneurysmal subarachnoid hemorrhage (SAH) is rarely reported.We describe here a case of intraoperative DI in a patient undergoing aneurysmal clipping surgery that posed a challenge for bot
Introduction: The global burden click here of thyroid disorders, especially hypothyroidism, is high and increasing.Prevalence studies of such disorders are limited in Nepal.The aim of this study was to find out the prevalence of hypothyroidism among patients visiting the Department of Biochemistry in the central laboratory of a tertiary care centre